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ZNHIT3蛋白抗体
ZNHIT3蛋白抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-ZNHIT3
Anti-zinc finger HIT-type containing 3 Antibody
半岛bd体育手机客户端 介绍
靶标:

ZNHIT3


半岛bd体育手机客户端 别名:

Hit1; PEHO; TRIP3; ZNHIT3; zinc finger HIT-type containing 3; zinc finger HIT-type containing 3; zinc finger HIT domain-containing protein 3; HNF-4a coactivator; TR-interacting protein 3; TRIP-3; thyroid hormone receptor interactor 3; thyroid receptor interacting protein 3; zinc finger, HIT domain containing 3; zinc finger, HIT type 3; ZNHIT3蛋白;


背景信息:
ZNHIT3 (zinc finger, HIT-type containing 3), also known as TRIP3 (thyroid receptor-interacting protein 3) or HNF-4a coactivator, is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR?-mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4?, and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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