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SLC28A1抗体
半岛bd体育手机客户端 介绍
靶标：
SLC28A1 半岛bd体育手机客户端 别名： CNT1； HCNT1； URCTU； SLC28A1； solute carrier family 28 member 1； solute carrier family 28 member 1； sodium/nucleoside cotransporter 1； Na(+)/nucleoside cotransporter 1； concentrative nucleoside transporter 1； sodium-coupled nucleoside transporter 1； solute carrier family 28 (concentrative nucleoside transporter), member 1； solute carrier family 28 (sodium-coupled nucleoside transporter), member 1； 背景信息：
function:Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.,polymorphism:Three variant forms of isoform 1 (A, B and C) are expressed in the kidney. All three variant forms have similar nucleoside transport activity.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in kidney.,
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