半岛bd体育手机客户端 介绍
靶标：
TAF1C 半岛bd体育手机客户端 别名： MGC:39976； SL1； TAFI110； TAFI95； TAF1C； TATA-box binding protein associated factor, RNA polymerase I subunit C； TATA-box binding protein associated factor, RNA polymerase I subunit C； TATA box-binding protein-associated factor RNA polymerase I subunit C； RNA polymerase I-specific TBP-associated factor 110 kDa； SL1, 110kD subunit； TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD； TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa； TATA box-binding protein-associated factor 1C； TATA-box binding protein associated factor, RNA polymerase I, C； TBP-associated factor 1C； transcription factor SL1； transcription initiation factor SL1/TIF-IB subunit C； TATA盒结合蛋白相关因子TAF1C； 背景信息：
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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