半岛bd体育手机客户端 介绍
靶标:
DHX16 半岛bd体育手机客户端 别名: DBP2; DDX16; NMOAS; PRO2014; PRP8; PRPF2; Prp2; DHX16; DEAH-box helicase 16; DEAH-box helicase 16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; ATP-dependent RNA helicase #3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH-box protein 16; RNA helicase; pre-mRNA processing factor 2; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; ATP-依赖的RNA解旋酶3; 背景信息:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009],
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