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杀伤细胞凝集素样受体C亚家族成员4抗体
半岛bd体育手机客户端 介绍
靶标:
KLRC4 半岛bd体育手机客户端 别名: NKG2-F; NKG2F; KLRC4; killer cell lectin like receptor C4; killer cell lectin like receptor C4; NKG2-F type II integral membrane protein; NK cell receptor F; NKG2-F-activating NK receptor; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; 杀伤细胞凝集素样受体C亚家族成员4; 背景信息:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member.
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