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锌指蛋白354A抗体
锌指蛋白354A抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-ZNF354A
Anti-zinc finger protein 354A Antibody
半岛bd体育手机客户端 介绍
靶标:

ZNF354A


半岛bd体育手机客户端 别名:

EZNF; HEL104; HKL1; KID-1; KID1; TCF17; ZNF354A; zinc finger protein 354A; zinc finger protein 354A; zinc finger protein 354A; epididymis luminal protein 104; transcription factor 17; zinc finger protein eZNF; 锌指蛋白354A;


背景信息:
ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Kr¨?ppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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