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叶酸转运蛋白(FOLT)抗体
半岛bd体育手机客户端 介绍
靶标:
SLC19A1 半岛bd体育手机客户端 别名: CHMD; FOLT; IFC-1; IFC1; MEGAF; REFC; RFC; RFC1; RFT-1; hRFC; hSLC19A1; SLC19A1; solute carrier family 19 member 1; solute carrier family 19 member 1; reduced folate transporter; folate transporter 1; intestinal folate carrier 1; placental folate transporter; reduced folate carrier 1; reduced folate carrier protein; reduced folate transporter 1; solute carrier family 19 (folate transporter), member 1; 叶酸转运蛋白(FOLT); 溶质载体家族蛋白19成员A1; 背景信息:
Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate.
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