半岛bd体育手机客户端
介绍 靶标: PTPRG 半岛bd体育手机客户端 别名: HPTPG; PTPG; R-PTP-GAMMA; RPTPG; PTPRG; protein tyrosine phosphatase receptor type G; protein tyrosine phosphatase receptor type G; receptor-type tyrosine-protein phosphatase gamma; H_RG317H01.1; protein tyrosine phosphatase gamma; protein tyrosine phosphatase, receptor type, gamma polypeptide; receptor type protein tyrosine phosphatase gamma; receptor tyrosine phosphatase gamma; receptor-type protein phosphatase gamma; 蛋白酪氨酸磷酸酶受体G(PTPRG); 背景信息: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008], 宿主:Rbt |
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