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核转录因子X盒结合蛋白1抗体
半岛bd体育手机客户端 介绍
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NFX1 半岛bd体育手机客户端 别名： NFX2； TEG-42； Tex42； NFX1； nuclear transcription factor, X-box binding 1； nuclear transcription factor, X-box binding 1； transcriptional repressor NF-X1； nuclear transcription factor, X box-binding protein 1； 核转录因子X盒结合蛋白1； 背景信息：
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008],
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