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肌凝蛋白磷酸酶2抗体
半岛bd体育手机客户端 介绍
靶标:
PPP1R12B 半岛bd体育手机客户端 别名: MYPT2; PP1bp55; PPP1R12B; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1 regulatory subunit 12B; myosin phosphatase target subunit 2; myosin phosphatase-targeting subunit 2; protein phosphatase 1, regulatory (inhibitor) subunit 12B; 肌凝蛋白磷酸酶2; 背景信息:
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
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