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杀伤细胞凝集素样受体C亚家族成员3抗体
半岛bd体育手机客户端 介绍
靶标:
KLRC3 半岛bd体育手机客户端 别名: NKG2-E; NKG2E; KLRC3; killer cell lectin like receptor C3; killer cell lectin like receptor C3; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor; killer cell lectin-like receptor subfamily C, member 3; 杀伤细胞凝集素样受体C亚家族成员3; 背景信息:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
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