半岛bd体育手机客户端 介绍
靶标:
ATP1A4 半岛bd体育手机客户端 别名: ATP1A1; ATP1AL2; ATP1A4; ATPase Na+/K+ transporting subunit alpha 4; ATPase Na+/K+ transporting subunit alpha 4; sodium/potassium-transporting ATPase subunit alpha-4; ATPase, Na+/K+ transporting, alpha 4 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; Na(+)/K(+) ATPase alpha-4 subunit; Na+/K+ ATPase 4; Na+/K+ ATPase, alpha-D polypeptide; Na,K-ATPase subunit alpha-C; sodium pump 4; sodium pump subunit alpha-4; sodium-potassium ATPase catalytic subunit alpha-4; sodium/potassium-transporting ATPase alpha-4 chain; 背景信息:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
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