重组新冠RBD单克隆抗体
型号: |
MAV101 |
品牌: |
卡梅德生物 |
参考价格: |
3500元/ug |
交货期: |
2-3天 |
产地: |
天津 |
包装与价格:
订货号 |
纯度规格 |
包装 |
价格(元) |
MAV101 |
|
100ug |
3500 |
半岛bd体育手机客户端 介绍
半岛bd体育手机客户端 编号 |
MAV101 |
半岛bd体育手机客户端 名称 |
Recombinant Human anti-COVID-19/SARS-CoV-2 RBD Monoclonal Antibody |
抗体亚型 |
IgG1 |
规格与价格 |
100ul/¥3,500; 500ul/¥9,000; 1000ul/¥16,000 |
克隆号 |
1G6 |
半岛bd体育手机客户端 别名 |
SARS-CoV-2 RBD antibody, 2019-nCoV, Coronavirus |
规格 |
100ul, 500ul |
物种 |
COVID-19 |
宿主 |
Human |
半岛bd体育手机客户端 应用 |
ELISA, Colloidal Gold, POCT, Neutralizaiton , Standard Positive Control |
内毒素水平 |
<0.1EU/ug determided by LAL method. |
缓冲体系 |
0.01M PBS, pH 7.4 |
免疫原 |
Native virus |
半岛bd体育手机客户端 背景 |
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19. A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus, which regulates its infectivity, pathogenesis and host range. SARS-CoV-2 and SARS-CoV recognize the same receptor—angiotensin-converting enzyme 2 (ACE2)—in humans. Researchers determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 (engineered to facilitate crystallization) in complex with ACE2. In comparison with the SARS-CoV RBD, an ACE2-binding ridge in SARS-CoV-2 RBD has a more compact conformation; moreover, several residue changes in the SARS-CoV-2 RBD stabilize two virus-binding hotspots at the RBD–ACE2 interface. These structural features of SARS-CoV-2 RBD increase its ACE2-binding affinity. Additionally, we show that RaTG13, a bat coronavirus that is closely related to SARS-CoV-2, also uses human ACE2 as its receptor. |
保存条件 |
This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
备注 |
This product is used for research use only. Not for human or diagnostic use. |
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卡梅德生物科技(天津)有限公司
电话:点击&查看400-621-6806 /022-82164980 13116038708
联系人: 张经理
邮编: 301700
地址: 天津市武清开发区畅源道国际企业社区 A5 号楼四层
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