Pentaethylene glycol di(p-toluenesulfonate)

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Pentaethylene glycol di(p-toluenesulfonate)

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

半岛bd体育手机客户端介绍

Pentaethylene glycol di(p-toluenesulfonate) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Cas No.	41024-91-3
别名	二对甲苯磺酸戊乙二醇,Penta(ethylene glycol) bis(p-toluenesulfonate); Bis-Tos-PEG5
分子式	C24H34O10S2
分子量	546.65
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.