APF 是一种荧光探针，可以选择性地、剂量依赖性地检测 ROS 中的某些物种，并且对自氧化具有高度抗性。
| Cas No. |
359010-70-1 |
| Canonical SMILES |
Nc1ccc(cc1)Oc1ccc2c(c1)Oc1cc(O)ccc1C12OC(=O)c2ccccc12 |
| 分子式 |
C26H17NO5 |
| 分子量 |
423.4 |
| 溶解度 |
DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS (pH 7.2)(1:3): .5 mg/ml |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively. |
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