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CYPMPO
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
CYPMPO图片
CAS NO: 934182-09-9
包装与价格：
包装 价格(元)
1mg 电议
5mg 电议
10mg 电议

半岛bd体育手机客户端 介绍
CYPMPO 是一种自旋捕获试剂。 CYPMPO 是一种环状 DEPMPO 型硝酮，其对羟基和超氧自由基的自旋捕获能力进行了评估。抗氧化和抗肿瘤活性。
Cas No. 934182-09-9
别名 2-(5,5-二甲基-2-氧代-1,3,2-二氧磷杂环己烷-2-基)-1-羟基-2-甲基-3,4-二氢-2H-1lambda5-吡咯-1-基,RR 071
化学名 5-(2,2-dimethyl-1,3-propoxycyclophosphoryl)-5-methyl-1-pyrroline N-oxide
Canonical SMILES O[N]1=CCCC1(C)P1(=O)OCC(C)(C)CO1
分子式 C10H18NO4P
分子量 247.2
溶解度 25mg/mL in ethanol or DMF, 20mg/mL in DMSO
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126℃), low hygroscopic properties, and long shelf-life in aqueous solutions offer significant practical advantages for use of CYPMPO over DEPMPO and DMPO.

Reference:
[1]. Kamibayashi, M., Oowada, S., Kameda, H., et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO). Free Radical Research 40(11), 1166-1172 (2006).
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