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Dichlorphenamide disodium
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dichlorphenamide disodium图片
CAS NO: 76382-13-3
包装与价格：
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 名称
Diclofenamide disodium
半岛bd体育手机客户端 介绍
Dichlorphenamide (Diclofenamide) disodium 是一种具有口服活性的，特异性，碳酸酐酶 ( carbonic anhydrase) 抑制剂，可以通过抑制眼睛中水的分泌，从而降低眼压，可用于青光眼的研究。
生物活性

Dichlorphenamide (Diclofenamide) disodium is an orally active, specific,carbonic anhydraseinhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research[1].
体内研究
(In Vivo)

Dichlorphenamide disodium can reduce IOP locally in male albino rabbits[1].

Animal Model: Male albino rabbits (approximately 2.5 kg)[1]
Dosage: 50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
Administration: Eye drop of 50 μL or oral gavage of 2 mg/kg or 6 mg/kg，5 hours
Result: Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration. And demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
Clinical Trial
分子量

351.14
Formula

C6H6Cl2N2Na2O4S2
CAS 号

76382-13-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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