Ritanserin - 半岛电竞官方网址

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Ritanserin

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

87051-43-2

包装与价格：

半岛bd体育手机客户端介绍

Ritanserin (R 55667) 是一种高效、相对选择性、口服活性、长效的 5-HT2 受体拮抗剂，IC50 为 0.9 nM，对组胺 H1、多巴胺 D2、肾上腺素 α1、肾上腺素 α2 受体的活性较低 .

Cas No.	87051-43-2
别名	利坦丝林,R 55667
化学名	6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
Canonical SMILES	FC1=CC=C(C=C1)/C(C(C=C2)=CC=C2F)=C3CCN(CCC4=C(C)N=C5SC=CN5C4=O)CC/3
分子式	C₂₇H₂₅F₂N₃OS
分子量	477.57
溶解度	DMF: 30 mg/ml,DMSO: 12.5 mg/ml,Ethanol: 2.5 mg/ml
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1]. Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine-H1 (IC50, 35 nM), Dopamine-D2 (IC50, 70 nM), Adrenergic-α1 (IC50, 97 nM), Adrenergic-α2 receptor (IC50, 150 nM)[1]. References: [1]. Leysen JE, et al. Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist. Mol Pharmacol. 1985 Jun;27(6):600-11.