Piclamilast (RP 73401) 是一种磷酸二酯酶 4 (PDE4) 抑制剂,在猪主动脉和嗜酸性粒细胞可溶性中的 IC50 值分别为 16 nM 和 2 nM。
Cas No. |
144035-83-6 |
别名 |
吡拉米司特,RP 73401; RPR 73401 |
化学名 |
3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide |
Canonical SMILES |
ClC1=C(C(Cl)=CN=C1)NC(C2=CC=C(C(OC3CCCC3)=C2)OC)=O |
分子式 |
C18H18Cl2N2O3 |
分子量 |
381.25 |
溶解度 |
<38.12mg/ml in DMSO |
储存条件 |
Store at RT |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |