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BACE-IN-1
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BACE-IN-1图片
CAS NO: 1254166-60-3
包装与价格:
包装 价格(元)
1mg 电议
5mg 电议
10mg 电议
20mg 电议

半岛bd体育手机客户端 介绍
BACE-IN-1(化合物13)是咪唑[1,2-a]吡啶衍的生物,其可以抑制β位点淀粉样蛋白前体蛋白切割酶(BACE),并且其可用于治疗涉及BACE的疾病,例如阿尔茨海默氏病。
Cas No. 1254166-60-3
Canonical SMILES O=C(C1=CN2C=C(Cl)C=CC2=N1)NC3=NC4=CC=C(OCC5=CC=CC=C5)C=C4N3
分子式 C22H16ClN5O2
分子量 417.85
溶解度 Soluble in DMSO
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.

[1]. Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1

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