LY288513 is a selective non-peptideCCK-Breceptor antagonist with an IC₅₀value of 16 nM. LY288513 produces an anxiolytic-like action in mice^[1][2][3].

IC50: 16 nM (CCK-B receptor)^[1]

LY288513 (10 nM; 2 days) suppresses the effects of CCK-8 on CD4⁺T cell subset-specific transcription factors^[2].

LY288513 (3, 10 mg/kg, i.p.; 10, 30 mg/kg, p.o.) produces an anxiolytic-like action in mice^[3].
LY288513 (1000 mg/kg, p.o.) potentiates the effects of a CNS depressant, slightly lowered body temperature, and had modest sedative effects only at the highest dose examined^[3].

436.30

C₂₂H₁₈BrN₃O₂

147523-65-7

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.