MeOSuc-Ala-Ala-Pro-Val-AMC - 半岛电竞官方网址

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MeOSuc-Ala-Ala-Pro-Val-AMC

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

72252-90-5

包装与价格：

半岛bd体育手机客户端介绍

MeOSuc-Ala-Ala-Pro-Val-AMC 是人类白细胞和猪胰弹性蛋白酶的荧光底物（Km:362 μ；M，Ex=380 nm，Em=460 nm）。

Cas No.	72252-90-5
别名	N-甲氧琥珀酰基-丙氨酰-丙氨酰-脯氨酰-缬氨酸-7-氨基-4-甲基香豆素
Canonical SMILES	COC(CCC(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(NC2=CC=C(C(C)=CC(O3)=O)C3=C2)=O)=O)=O)C)=O)C)=O)=O
分子式	C₃₁H₄₁N₅O₉
分子量	627.7
溶解度	DMF: 20 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 16 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low fluorescence (excitation: 355-380 nm; emission 440-460 nm) that demonstrates a linear increase in fluorescence in the presence of elastase. This peptidyl-AMC substrate detects as little as 11 pM human leukocyte elastase and 18 pM porcine pancreatic elastase.