Paraherquamide A - 半岛电竞官方网址

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Paraherquamide A

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

77392-58-6

包装与价格：

半岛bd体育手机客户端介绍

Paraherquamide A (PNU-97333) 是一种有毒代谢物，可从 Penicillium paraherquei 中分离出来。

Cas No.	77392-58-6
别名	对郝喹酰胺A,PNU-97333
Canonical SMILES	CC(C=CO1)(C)OC2=C1C(NC([C@]34C[C@](CN(CC[C@]5(O)C)[C@]5(C6=O)C7)(N6C)[C@]7([H])C3(C)C)=O)=C4C=C2
分子式	C₂₈H₃₅N₃O₅
分子量	493.6
溶解度	DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 ?g/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).