Sulfadoxine D3 is a deuterium labeledSulfadoxine(HY-B0439). Sulfadoxine is a sulfonamide that is used, usually in combination withPyrimethamine(HY-18062), for multidrug-resistantPlasmodiumfalciparumandP. vivaxinhibition. Unlike PYR, Sulfadoxine has no impact onHIVreplication or MT-2 cell cycle progression. But also Sulfadoxine exhibits suppression on respiratory, and urinary tract infections^[1][2][3][4].

磺胺多辛 (0-100 μM;7 d) 对 MT-2 细胞中 HIV-1 的复制无影响^[4].
磺胺多辛 (100 μM;48 h) 对 MT-2 细胞 S 期积累的诱导无影响^[4].

磺胺多辛 (0.1, 0.3, 10 mg/kg/d; 口服; 每日1次, 连用 3天) 与阿奇霉素 (30 mg/kg/d; 口服; 每日1次, 连用 3天)，能够抑制小鼠疟疾模型中的血期寄生虫或约氏疟原虫子孢子^[5].

313.35

C₁₂H₁₁D₃N₄O₄S

1262770-70-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.