Diethyltoluamide 鏄┍铏墏涓渶甯歌鐨勬椿鎬ф垚鍒嗭紝淇濇姢鐨偆锛岄槻姝㈣殜瀛愶紝鎵佽櫛锛岃殼锛屾仚铻紝姘磋洯锛屽強鍏朵粬鏄嗚櫕鐨勫彯鍜€侟/div>
| 鐢熺墿娲绘€?/td> |
Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects.
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| IC50& Target |
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| Clinical Trial |
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| 鍒嗗瓙閲廃/td> |
|
| 鎬х姸 |
|
| Formula |
|
| CAS 鍙饵/td> |
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| 涓枃鍚嶇О |
|
| 杩愯緭鏉′欢 |
Room temperature in continental US; may vary elsewhere.
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| 鍌ㄥ瓨鏂瑰紡 |
| Pure form |
-20°C |
3 years |
|
4°C |
2 years |
| In solvent |
-80°C |
6 months |
|
-20°C |
1 month |
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| 婧惰В鎬ф暟鎹?/td> |
In Vitro:
DMSO : 鈮 100 mg/mL(522.82 mM)
H2O : 2 mg/mL(10.46 mM;Need ultrasonic)
*"鈮? means soluble, but saturation unknown.
閰嶅埗鍌ㄥ娑秉/div>
| 娴撳害婧跺墏浣撶Н璐ㄩ噺 |
1 mg |
5 mg |
10 mg |
| 1 mM |
5.2282 mL |
26.1411 mL |
52.2821 mL |
| 5 mM |
1.0456 mL |
5.2282 mL |
10.4564 mL |
| 10 mM |
0.5228 mL |
2.6141 mL |
5.2282 mL |
*
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鍌ㄥ娑茬殑淇濆瓨鏂瑰紡鍜屾湡闄愶細-80鈩? 6 months; -20鈩? 1 month銆侟/span>-80鈩 鍌ㄥ瓨鏃讹紝璇峰湪 6 涓湀鍐呬娇鐢紝-20鈩 鍌ㄥ瓨鏃讹紝璇峰湪 1 涓湀鍐呬娇鐢ㄣ€侟/span>
In Vivo:
璇锋牴鎹偍鐨勫疄楠屽姩鐗╁拰缁欒嵂鏂瑰紡閫夋嫨閫傚綋鐨勬憾瑙ｆ柟妗堛€備互涓嬫憾瑙ｆ柟妗堥兘璇峰厛鎸夌収In Vitro鏂瑰紡閰嶅埗婢勬竻鐨勫偍澶囨恫锛屽啀渚濇娣诲姞鍔╂憾鍓傦細
鈥斺€斾负淇濊瘉瀹為獙缁撴灉鐨勫彲闈犳€э紝婢勬竻鐨勫偍澶囨恫鍙互鏍规嵁鍌ㄥ瓨鏉′欢锛岄€傚綋淇濆瓨锛涗綋鍐呭疄楠岀殑宸ヤ綔娑诧紝寤鸿鎮ㄧ幇鐢ㄧ幇閰嶏紝褰撳ぉ浣跨敤锛 浠ヤ笅婧跺墏鍓嶆樉绀虹殑鐧近br/>鍒嗘瘮鏄寚璇ユ憾鍓傚湪鎮ㄩ厤鍒剁粓婧舵恫涓殑浣撶Н鍗犳瘮锛涘鍦ㄩ厤鍒惰繃绋嬩腑鍑虹幇娌夋穩銆佹瀽鍑虹幇璞★紝鍙互閫氳繃鍔犵儹鍜?鎴栬秴澹扮殑鏂瑰紡鍔╂憾
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1.
璇蜂緷搴忔坊鍔犳瘡绉嶆憾鍓傦細 PBS
Solubility: 100 mg/mL (522.82 mM); Clear solution; Need ultrasonic
*浠ヤ笂鎵€鏈夊姪婧跺墏閮藉彲鍦ㄦ湰缃戠珯閫夎喘銆侟/span>
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