Halofantrine hydrochloride(SKF-102886) - 半岛电竞官方网址

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Halofantrine hydrochloride(SKF-102886)

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

36167-63-2

包装与价格：

半岛bd体育手机客户端介绍

Halofantrine hydrochloride (SKF-102886) (SKF-102886) 是一种延迟整流钾电流的阻滞剂，通过抑制人类-ether-a-go-go-related gene (HERG) 通道和一种有效的抗疟化合物。

Cas No.	36167-63-2
别名	盐酸卤泛群,SKF-102886; WR-171669 hydrochloride
Canonical SMILES	OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31.[H]Cl
分子式	C₂₆H₃₁Cl₃F₃NO
分子量	536.88
溶解度	DMSO: 30 mg/mL (55.88 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2]. [1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.