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Cefotiam
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Cefotiam图片
CAS NO: 61622-34-2
包装与价格：
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 名称
SCE-963
半岛bd体育手机客户端 介绍
Cefotiam (SCE-963) 是肠外头孢菌素类抗生素。Cefotiam 对革兰氏阳性菌和革兰氏阴性菌具有广谱活性。
生物活性

Cefotiam (SCE-963) is a parenteral cephalosporinantibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1][2].
IC50& Target

β-lactam
体外研究
(In Vitro)

Cefotiam (SCE-963; 0-6.25μg/mL; 8 h) has antibacterial activity with a MIC value of 1.56 μg/mL forP. mirabilisIFO 3849[1].
Cefotiam (0-6.25μg/mL; 8 h) has highly active against bothStaph. aureus(27 strains, MIC values of 0.5-1 μg/mL) andStaph. albus(8 strains, MICs 0.25-0.5 μg/mL). All 29 strains ofhaemolytic streptococci, 9 strains ofpneumococciand 6 strains ofStreptococcus viridanswith the MIC values of in the range 0.06-4 μg/mL[2].
体内研究
(In Vivo)

Cefotiam (SCE-963; 12.5-800 mg/kg; i.h.; twice a day for 5 d) can cure urinary tract infection withP. mirabilisin mice to reduce or complete eradicate bacteria in the bladder walls and kidneys[1].

Animal Model: Female CF1/b mice withP. mirabilisxenograft[1]
Dosage: 12.5, 25, 50, 100, 200, 400 and 800 mg/kg
Administration: Subcutaneous injection; twice a day, for 5 days
Result: Reduced or complete eradicated bacteria in the bladder walls and kidneys of mice sacrificed the day after treatment was terminated.
Clinical Trial
分子量

525.63
Formula

C18H23N9O4S3
CAS 号

61622-34-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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