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DBCO-PEG4-Val-Cit-PAB-MMAF
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DBCO-PEG4-Val-Cit-PAB-MMAF图片
CAS NO: 2244602-23-9
包装: 10mg
市场价: 10800元

半岛bd体育手机客户端 介绍
DBCO-PEG4-Val-Cit-PAB-MMAF 由可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker (DBCO-PEG4-Val-Cit-PAB) 和 MMAF 组成,MMAF 是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂。DBCO-PEG4-Val-Cit-PAB-MMAF 可用于合成抗体偶联药物 (ADC)。
Cas No. 2244602-23-9
分子式 C88H126N12O20
分子量 1672.01
溶解度 DMSO : 250 mg/mL (149.52 mM; Need ultrasonic)
储存条件 Store at -20°C, stored under nitrogen
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

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