endo-BCN-PEG3-mal 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. |
2141976-33-0 |
分子式 |
C26H37N3O8 |
分子量 |
519.59 |
溶解度 |
DMSO : 50 mg/mL (96.23 mM; ultrasonic and warming and heat to 60°C) |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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