Lemborexant (E-2006) 是一种可逆、竞争性和口服活性的食欲素 OX1 和 OX2 受体双重拮抗剂，IC50 值分别为 6.1 nM 和 2.6 nM。
| Cas No. |
1369764-02-2 |
| 别名 |
莱博雷生,E-2006 |
| Canonical SMILES |
O=C([C@H]1[C@@](C2=CC=CC(F)=C2)(COC3=CN=C(C)N=C3C)C1)NC4=NC=C(F)C=C4 |
| 分子式 |
C22H20F2N4O2 |
| 分子量 |
410.42 |
| 溶解度 |
DMSO : ≥ 30 mg/mL (73.10 mM) |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Lemborexant (E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development for treatment of insomnia. |
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