您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 半岛bd体育手机客户端 库> Dolasetron Mesylate hydrate
立即咨询
咨询类型:
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
Dolasetron Mesylate hydrate
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dolasetron Mesylate hydrate图片
CAS NO: 878143-33-0
包装与价格:
包装 价格(元)
10mM (in 1mL DMSO) 电议
100mg 电议
200mg 电议

半岛bd体育手机客户端 介绍
Dolasetron(MDL-73147)是5-HT3受体拮抗剂,用于只治疗化疗引起的恶心和呕吐症状。
Cas No. 878143-33-0
别名 甲磺酸多拉司琼,MDL-73147EF hydrate
Canonical SMILES O=C(C1=CNC2=C1C=CC=C2)O[C@@H]3C[C@@](CC4C5)([H])[N@](CC4=O)[C@@]5([H])C3.O=S(C)(O)=O.O
分子式 C20H26N2O7S
分子量 438.49
溶解度 DMSO : ≥ 39 mg/mL (88.94 mM)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

[1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77.

Baidu
map