PSB-12379 disodium - 半岛电竞官方网址

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PSB-12379 disodium

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

半岛bd体育手机客户端介绍

PSB-12379 disodium 是一种核苷类似物，是一种有效的 Ecto-5'-Nucleotidase( CD73) 抑制剂， K_is 值为 9.03 nM (鼠) 和 2.21 nM (人)。

生物活性	PSB-12379 disodium, a nucleotide analogue, is a potentEcto-5'-Nucleotidase(CD73) inhibitor withK_is of 9.03 nM (rat) and 2.21 nM (human)^[1]^[2].
IC₅₀& Target	Ki: 9.03 nM (rat), 2.21 nM (human) (Ecto-5’-Nucleotidase)^[1].
体内研究 (In Vivo)	Metabolism: Only a small percentage (<23%) of PSB-12379 (10g) is metabolized under the applied conditions, while >77% of the compounds are recovered unchanged after a long incubation for 8 h. PSB-12379 (10g) is somewhat less stable, and 56% are metabolized within 8 h. Hydrolytic cleavage of the glycosidic bond, which is a typical phase I reaction of nucleosides and nucleotides, was observed as the main reaction^[1].
分子量	573.34
Formula	C₁₉H₂₃N₅Na₂O₉P₂
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.