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BIM-26226
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
BIM-26226图片
CAS NO: 136207-23-3
包装与价格：
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 介绍
BIM-26226 是一种胃泌素释放肽，是一种强效选择性的 bombesin receptor拮抗剂。 BIM-26226 抑制 BN 或 GRP 刺激的淀粉酶释放， IC50值在纳摩尔范围内。BIM-26226 可用于癌症研究。
生物活性

BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist ofbombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release withIC50s in the nanomolar range. BIM-26226 can be used for the research ofcancer[1][2].
IC50& Target

bombesin receptor[1]
分子量

1075.09
Formula

C49H63F5N12O10
CAS 号

136207-23-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:

H2O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3. Recommended solution:

Overall charge of peptide Details
Negative (<0) 1. Try to dissolve the peptide in water first.
2. If water fails, add NH4OH (<50 μL).
3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1. Try to dissolve the peptide in water first.
2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
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