AB-729 是一种siRNA,通过RNA 干扰 (
RNAi)抑制病毒复制并减少
HBV抗原。AB-729 与 N-乙酰半乳糖胺 (GalNAc) 配体的三聚体结合,通过去唾液酸糖蛋白受体 (ASGR) 促进肝细胞摄取 。
生物活性 |
AB-729 is a siRNA specifically designed to inhibit viral replication and reducesHBVantigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
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Clinical Trial |
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CAS 号 |
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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