Ro 0437626 是一种选择性嘌呤能 (P2X1) 受体拮抗剂 (IC50 = 3 μM)，但对 P2X2、P2X3 和 P2X2/3 受体的亲和力较低 (IC50 >100 μM)。
| Cas No. |
134362-79-1 |
| 化学名 |
N-((R)-1-(((2S,3R,4R)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl)amino)-1-oxo-3-(thiazol-4-yl)propan-2-yl)-1H-benzo[d]imidazole-2-carboxamide |
| Canonical SMILES |
O[C@@H]([C@@H]([C@H](CC1CCCCC1)NC([C@@H](CC2=CSC=N2)NC(C3=NC4=CC=CC=C4N3)=O)=O)O)C5CC5 |
| 分子式 |
C27H35N5O4S |
| 分子量 |
525.66 |
| 溶解度 |
<52.57mg/ml in ethanol;<52.57mg/ml in DMSO |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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