187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allostericneural Wiskott-Aldrich syndrome protein (N-WASP)inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with anIC₅₀of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation ofArp2/3complex by N-WASP by stabilizing the autoinhibited state of the protein^[1][2].

1898.13

C₉₈H₁₂₃F₃N₁₈O₁₈

Cyclo[Gln-Lys-{d-Phe}-{d-Pro}-{d-Phe}-Phe-{d-Pro}-Gln-Lys-{d-Phe}-{d-Pro}-{d-Phe}-Phe-{d-Pro}]

Cyclo[QK-{d-Phe}-{d-Pro}-{d-Phe}-F-{d-Pro}-QK-{d-Phe}-{d-Pro}-{d-Phe}-F-{d-Pro}]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.