Ac-FEID-CMK 是一种有效的斑马鱼特异性
GSDMEb衍生肽抑制剂。Ac-FEID-CMK 可减轻感染性休克的死亡率和肾损伤。Ac-FEID-CMK 在体内可抑制焦亡,减轻败血性 AKI (急性肾损伤)。Ac-FEID-CMK 可抑制 caspy2 介导的非典型炎症小体通路。
生物活性 |
Ac-FEID-CMK is a potent zebrafish-specificGSDMEb-derived peptideinhibitor. Ac-FEID-CMK can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK inhibitspyroptosisand attenuates septic AKI (acute kidney injury)in vivo. Ac-FEID-CMK can suppress the caspy2-mediated noncanonical inflammasome pathway[1].
|
分子量 |
|
Formula |
|
运输条件 |
Room temperature in continental US; may vary elsewhere.
|
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
|