Ac-FEID-CMK TFA 是一种有效的斑马鱼特异性
GSDMEb衍生肽抑制剂。Ac-FEID-CMK TFA 可减轻感染性休克的死亡率和肾损伤。Ac-FEID-CMK TFA 在体内可抑制焦亡,减轻败血性 AKI (急性肾损伤)。Ac-FEID-CMK TFA 可抑制 caspy2 介导的非典型炎症小体通路。
生物活性 |
Ac-FEID-CMK TFA is a potent zebrafish-specificGSDMEb-derived peptideinhibitor. Ac-FEID-CMK TFA can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK TFA inhibitspyroptosisand attenuates septic AKI (acute kidney injury)in vivo. Ac-FEID-CMK TFA can suppress the caspy2-mediated noncanonical inflammasome pathway[1].
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Formula |
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
-20°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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