DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degradesABL1, ABL2, BLK, CDK11B,CDK4, CSK,EPHA3, FER, GAK,LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9,MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B,RIPK1, RPS6KA1, RPS6KA3,SIK2,SIK3, STK35, TNK2, andULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity^[1].

1144.31

Solid

C₅₉H₆₈F₃N₁₃O₆S

2769753-53-7

Room temperature in continental US; may vary elsewhere.

DMSO : 60 mg/mL(52.43 mM;Need ultrasonic)

请根据半岛bd体育手机客户端 在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的半岛bd体育手机客户端 失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。