3-O-Methyl-N-acetyl-D-glucosamine 是 N-乙酰氨基葡萄糖激酶的有效抑制剂。
| Cas No. |
94825-74-8 |
| 别名 |
2-乙酰氨基-2-脱氧-3-O-甲基D-D-吡喃葡萄糖,3-O-Methyl-GlcNAc |
| Canonical SMILES |
OC1[C@H](NC(C)=O)C(OC)[C@@H](O)[C@@H](CO)O1 |
| 分子式 |
C9H17NO6 |
| 分子量 |
235.2 |
| 溶解度 |
DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 ?M in rat liver, respectively, in vitro). |
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