肉豆蔻脑酸是锯齿棕提取物中的一种细胞毒性成分,可诱导人前列腺 LNCaP 细胞凋亡和坏死。
Cas No. |
544-64-9 |
别名 |
肉豆蔻酸; 肉豆蔻油酸 |
Canonical SMILES |
OC(CCCCCCC/C=C\CCCC)=O |
分子式 |
C14H26O2 |
分子量 |
226.4 |
溶解度 |
DMF: 3 mg/ml,DMSO: 2.5 mg/ml,Ethanol: miscible,PBS (pH 7.2): 2 mg/ml |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
Myristoleic acid is a monounsaturated fatty acid found in the fruit extract of S. repens and in dairy extracts. It induces apoptosis and necrosis in human prostate cancer LNCaP cells at a rate of 8.8% and 8.1%, respectively. Myristoleic acid inhibits C. albicans germination in vitro with a minimal inhibitory concentration (MIC) of 9 µM. Furthermore, myristoleic acid inhibits osteogenesis in vitro via interference with cytoskeletal rearrangement and prevents RANKL-induced bone loss and osteoclast formation in mice. |