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Furazolidone
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Furazolidone图片
CAS NO: 67-45-8
包装与价格:
包装 价格(元)
10mM (in 1mL DMSO) 电议
1g 电议

半岛bd体育手机客户端 介绍
Furazolidone是硝基呋喃衍生物,具有抗原虫和抗菌活性,抑制AML1-ETO转化细胞,IC50为12.7μM。
Cas No. 67-45-8
别名 呋喃唑酮
Canonical SMILES O=C1OCCN1/N=C/C2=CC=C([N+]([O-])=O)O2
分子式 C8H7N3O5
分子量 225.16
溶解度 DMSO : 10 mg/mL (44.41 mM);Water :< 0.1 mg/mL (insoluble)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.Target: Antibacterial Furazolidone is a novel therapeutic strategy in AML patients. Furazolidone can Inhibit the bone-marrow transformation mediated by a series of leukemia fusion proteins. Furazolidone significantly inhibits proliferation of AML cell lines. Furazolidone induces apoptosis of the AML leukemic cells treatment with Furazolidone induces differentiation of AML cell lines.

[1]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335.

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