Diclofenac Acyl-β-D-Glucuronide - 半岛电竞官方网址

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Diclofenac Acyl-β-D-Glucuronide

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

64118-81-6

包装与价格：

半岛bd体育手机客户端介绍

Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat.

Cas No.	64118-81-6
别名	双氯芬酸酰基-Β-D-葡糖苷酸
Canonical SMILES	ClC1=CC=CC(Cl)=C1NC2=C(CC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=O)C=CC=C2
分子式	C₂₀H₁₉Cl₂NO₈
分子量	472.3
溶解度	DMSO: Soluble,Methanol: Soluble
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. Diclofenac acyl-β-D-glucuronide is acutely toxic in vitro, suggesting it may play a role in the hepatotoxicty of diclofenac in vivo. Diclofenac acyl-β-D-glucuronide binds to organic anion transporters (OATs; Km = 60.2, 8.6, 112, and 103.9 ?M for OAT1-4, respectively) as well as multi-drug resistance proteins. High levels of diclofenac are found in waste water treatment plant samples, which may be due to the back-transformation of diclofenac acyl-β-D-glucuronide to diclofenac.