Seneciphylline - 半岛电竞官方网址

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Seneciphylline

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

480-81-9

包装与价格：

半岛bd体育手机客户端介绍

Seneciphylline 是千里光植物中的一种有毒的吡咯里西啶生物碱。 Seneciphylline 显着增加环氧化物水合酶和谷胱甘肽-S-转移酶的活性，但导致细胞色素 P-450 和相关单加氧酶活性降低。

Cas No.	480-81-9
别名	千里光菲灵碱
Canonical SMILES	O=C(/C(CC([C@@]1(C)O)=C)=C\C)O[C@]2([H])CCN3[C@]2([H])C(COC1=O)=CC3
分子式	C₁₈H₂₃NO₅
分子量	333.4
溶解度	DMF: 5 mg/ml,DMSO: 2 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 0.1 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Seneciphylline is an alkaloid that has been found F. japonicum and has diverse biological activites. It induces autophagy and decreases viability of Huh7.5 cells in a concentration-dependent manner. Seneciphylline is also cytotoxic to HepG2 cells (IC20 = 0.66 mM). Dietary administration of seneciphylline induces sex-linked recessive lethality in male Drosophila. Seneciphylline (80 mg/kg) increases the activity of epoxide hydrase and glutathione-S-transferase and decreases activity of cytochrome P450 and aminopyrine demethylase in rat liver.