Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin.
Cas No. |
879292-24-7 |
别名 |
赛洛多辛β-D-葡萄糖苷酸钠盐 |
Canonical SMILES |
C[C@H](CC1=CC(C(N)=O)=C(N(CCCO[C@@H]2O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]2O)CC3)C3=C1)NCCOC4=C(OCC(F)(F)F)C=CC=C4.[Na+] |
分子式 |
C31H39F3N3O10?Na |
分子量 |
693.6 |
溶解度 |
Methanol: slightly soluble |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg. |