描述
| Gene ID: |
7471 |
Accession #: |
P04628 |
| Alternate Names: |
Human WNT-1, WNT-1, WNT1, WNT 1, h-WNT-1, rh-WNT-1, recombinant human WNT-1, recombinant WNT-1, WNT |
| Source: |
Escherichia Coli. |
M.Wt: |
38.4 kDa |
| Appearance: |
Lyophilized powder |
Storage: |
Store at -20℃ |
| Formulation: |
Sterile filtered and lyophilized with no additives. |
| Solubility: |
Reconstitute in water to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffers. |
| Shipping Condition: |
Blue ice. |
Handling: |
Centrifuge the vial prior to opening. |
| Usage: |
For Research Use Only! Not to be used in humans. |
资料参考
The WNT gene family compose of structurally related genes that encode secreted signaling proteins. These proteins have been involved in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Recombinant human WNT-1 is a 38.4 kDa, non-glycosylated protein containing 343 amino acid residues. Elevated levels of WNT proteins are associated with tumorigenesis and present in numerous human breast cancers.
生物活性
| Determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The concentration of Human BMP-2 is 200 ng/ml. |
| ED50 |
=1.5-2.5 ng/ml. |
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