氟米龙是一种合成的糖皮质激素，是一种具有抗炎和抗过敏特性的糖皮质激素受体激动剂。
| Cas No. |
426-13-1 |
| 别名 |
氟米龙 |
| Canonical SMILES |
O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(C)=O)=C1 |
| 分子式 |
C22H29FO4 |
| 分子量 |
376.5 |
| 溶解度 |
DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 |
4°C, away from moisture and light |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay). Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment. Formulations containing fluorometholone have been used for the treatment of eye inflammation. |
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