米索前列醇（游离酸）是米索前列醇的一种活性代谢物。
| Cas No. |
112137-89-0 |
| 别名 |
米索前列醇酸 |
| Canonical SMILES |
O[C@H]1[C@H](/C=C/CC(C)(O)CCCC)[C@@H](CCCCCCC(O)=O)C(C1)=O |
| 分子式 |
C21H36O5 |
| 分子量 |
368.5 |
| 溶解度 |
DMF: >100 mg/ml (from PGE1),DMSO: >50 mg/ml (from PGE1),Ethanol: >50 mg/ml (from PGE1),PBS pH 7.2: 1.67 mg/ml (from PGE1) |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Misoprostol is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 ?g/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 ?M), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid. |
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