| CAS NO: | 137160-11-3 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 137160-11-3 |
| 别名 | 阿替加奈,CNS 1102 |
| Canonical SMILES | N=C(N(C)C3=CC=CC(CC)=C3)NC1=C2C(C=CC=C2)=CC=C1.Cl |
| 分子式 | C20H21N3.HCl |
| 分子量 | 339.86 |
| 溶解度 | DMSO: 100 mM,Water: 50 mM |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | Potent and noncompetitive NMDA receptor antagonist (IC50 = 36 nM). Exhibits >70-fold selectivity for NMDA receptor over σ receptor. Neuroprotective in a rat model of focal ischemia. Reddy et al (1994) Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist. J.Med.Chem. 37 260 PMID:8295213 |Sch?bitz et al (2000) The N-MthD.-aspartate antagonist CNS 1102 protects cerebral gray and white matter from ischemic injury following temporary focal ischemia in rats. Stroke 31 1709 PMID:10884477 |
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