Coptisine Sulfate 是一种来自中国金线的生物碱，是一种高效的非竞争性 IDO 抑制剂，其 Ki 值为 5.8 μM，IC50 值为 6.3 μM。
| Cas No. |
1198398-71-8 |
| 别名 |
硫酸黄连碱 |
| Canonical SMILES |
O=S(O[O-])=O.C1(OCO2)=C2C=C(C(C=C(C=CC3=C4OCO3)C4=C5)=[N+]5CC6)C6=C1 |
| 分子式 |
C19H14NO4.HO4S |
| 分子量 |
372.09 |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM[1]. References:
[1]. Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302. |
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